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Patients must have histopathological documentation of prostate cancer confirmed in the Pathology Department of the Clinical Center at the National Institutes of Health or the National Naval Medical Center prior to starting this study.

The authors suggest that patients utilize birth control while on this medication; regularly testing urine or serum human chorionic gonadotropin (HCG) along with other laboratory tests, such as potassium and creatinine, is appropriate.

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Chewable tablets should be taken with food or water, as they might cause a burning feeling in the mouth or throat.

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Two patients withdrew from therapy, one for personal reasons and one because a paraspinal mass developed.

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Seborrheic dermatitis: apply to affected area twice daily for 4 weeks or until clinical clearing.

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